What is an NSAID?

• A. Non-Steroidal Anti-Inflammatory Drug
• B. Non-Steroidal Antagonist Drug
• C. Neuro-Suppressive Anti-Inflammatory Drug
• D. Non-Synthetic Anti-Inflammatory Drug

Answer: (A)

Non-Steroidal Anti-Inflammatory Drug reduces inflammation, pain, and fever by blocking prostaglandin production through inhibition of the cyclooxygenase (COX) enzymes. The “non-steroidal” part distinguishes them from corticosteroids, which are steroid-based anti-inflammatories. This mechanism explains why NSAIDs help with inflammatory pain—by dialing down prostaglandins that drive inflammation and sensitization of nerves. They’re widely used for conditions like arthritis, headaches, and general aches. Common examples include ibuprofen, naproxen, and aspirin. Because prostaglandins also protect the stomach lining and support kidney function, NSAIDs can cause GI upset and renal effects in some people, so they’re used with caution in those at risk. The other phrasings aren’t correct definitions: they don’t describe the enzyme inhibition and the non-steroidal nature that define NSAIDs.